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Serum Protein Electrophoresis (by Bromocresol Green)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood serum, often used to identify abnormalities in protein levels that may suggest conditions like multiple myeloma, liver disease, or other disorders.

Quick summary

["This test helps doctors check protein balance in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14425-3
Short code
Globulin Amn-mCnc
Synonyms
Globulin Amn-mCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Serum protein electrophoresis separates blood proteins into distinct fractions (e.g., albumin, globulins, and other proteins) using an electrical charge. Bromocresol Green is a dye used to visualize these fractions during electrophoresis. This helps identify any unusual patterns that might indicate health concerns.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if they suspect conditions affecting protein levels, such as chronic infections, autoimmune diseases, kidney disease, or certain cancers. It’s also used to monitor treatment progress in patients with known protein-related disorders.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The serum portion is separated and analyzed using electrophoresis to separate proteins by size and charge. Results are interpreted by comparing the protein distribution to expected patterns.

What Are Common Findings?

Abnormal results may show shifts in protein bands, such as elevated or low levels of specific proteins. For example, a high globulin level might suggest inflammation or autoimmune disease, while unusual spikes could indicate conditions like multiple myeloma.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in diagnosing and managing conditions that alter protein synthesis, distribution, or breakdown in the body. It provides valuable insights for tailoring treatment plans, especially in cases involving chronic diseases or cancer.

Short name

Protein Electrophoresis (BCG)

Frequently asked questions

What does a high or low protein electrophoresis result mean?
A high or low result alone doesn’t diagnose a specific condition. Instead, it signals a need for further evaluation by your doctor to explore potential causes, such as infections, liver/kidney issues, or other systemic diseases.
How often should I get this test?
Your doctor will determine the frequency based on your health status, symptoms, or ongoing treatment. Regular monitoring may be needed if you have a known condition affecting proteins, such as multiple myeloma or lupus.
Can lifestyle changes affect protein electrophoresis results?
While diet and hydration can influence overall protein levels, protein electrophoresis results are primarily about the distribution of specific proteins. Your doctor may recommend adjustments to your diet or lifestyle if they suspect dietary factors contribute to your condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy