Serum Protein Electrophoresis (Globulin Fraction)
This test measures the different types of proteins in your blood, focusing on the portion called globulin. It helps identify imbalances that may indicate conditions like infections, autoimmune diseases, or certain cancers.
["This test helps doctors diagnose and monitor conditions affecting protein balance in your blood."]
Key facts at a glance
- LOINC
- 13536-8
- Short code
- Globulin Plas-mCnc
- Synonyms
- Globulin Plas-mCnc
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test separates blood proteins into groups (albumin, globulin, and others) using a technique called electrophoresis. Globulin is one of the key protein groups, which includes antibodies and other proteins that support immune function, blood clotting, and transport of substances in the body.
Why It’s Done
Doctors may order this test to investigate symptoms like fatigue, swelling, unexplained weight loss, or recurring infections. It can also help diagnose conditions such as multiple myeloma, lymphoma, or chronic liver disease.
Sample Collection and Preparation
A small blood sample is drawn from your arm. The blood is then processed to separate serum (the liquid part after clotting) and analyzed for protein composition. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.
Common Conditions Linked to Results
Abnormal globulin levels can signal conditions like autoimmune diseases (e.g., rheumatoid arthritis), infections, or cancers. High globulin may suggest immune system activity, while low globulin could indicate liver disease or malnutrition.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is critical for diagnosing and managing conditions that affect protein metabolism. It provides insight into overall protein health, immune function, and potential underlying diseases that may require further testing or treatment.
Short name
Protein Electrophoresis
Frequently asked questions
How long does it take to get my results back?
What does it mean if my globulin levels are high?
Do I need to fast before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy