Serum Protein Electrophoresis (Globulins)
This test measures the different types of proteins in your blood, including globulins, which help support immunity and maintain fluid balance.
["Understanding your protein composition can help identify potential health concerns like infections, autoimmune conditions, or protein disorders."]
Key facts at a glance
- LOINC
- 2336-6
- Short code
- Globulin Ser-mCnc
- Synonyms
- Globulin Ser-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 17
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is a Globulin Profile?
Globulins are a group of proteins in your blood that include antibodies (which fight infections), transport proteins (like lipoproteins), and other immune-related proteins. This test separates these proteins based on size and charge using an electrophoresis method, allowing for detailed analysis of their distribution.
Why Might You Need This Test?
Your doctor may order this test if you have symptoms like fatigue, frequent infections, swelling, or unexplained weight changes. It’s also used to monitor conditions like multiple myeloma, lymphoma, or chronic infections.
How Is the Test Performed?
A small blood sample is drawn from your arm. The serum (liquid part of blood after clotting) is then analyzed in a lab to separate proteins by size. Results show the relative amounts of different protein fractions, including globulins.
What Do the Results Mean?
Results typically show the percentage or concentration of globulins compared to other proteins (albumin, globulins, and total protein). Abnormal patterns may indicate conditions affecting protein production, immune function, or fluid balance.
Reference range
NCBI: NSE 0-17 ng/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Globulin Profile (Serum Electrophoresis)
Frequently asked questions
What are the most common reasons for this test?
How long does it take to get results?
Can lifestyle changes affect globulin levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy