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Glucagon, Serum (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucagon, a hormone produced by special cells in your pancreas, in your blood. Glucagon helps regulate blood sugar levels by prompting your liver to release glucose.

Quick summary

["Glucagon helps control how your body uses sugar, and low or high levels may signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95094-9
Short code
Glucagon 2.5h p meal SerPl-mCnc
Synonyms
Glucagon 2.5h p meal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like unexplained low blood sugar (hypoglycemia), unexplained high blood sugar (hyperglycemia), or conditions such as diabetes, pancreatic issues, or gastrointestinal disorders. It may also be used to diagnose or monitor rare metabolic disorders.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for 8–12 hours before the test if instructed by your healthcare provider. Bring any medications you’re currently taking to your appointment.

How the Test Is Performed

A blood sample will be drawn from a vein in your arm by a healthcare professional. The sample is then sent to a lab for analysis using a sensitive immunoassay method to measure glucagon concentration.

What the Results Mean

Results are compared to a reference range specific to your lab, but they don’t provide absolute values for normal or abnormal levels. Your doctor will interpret the results in the context of your symptoms, medical history, and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormally low glucagon levels may indicate conditions like severe liver disease, pancreatic tumors, or certain genetic disorders. High levels could suggest pancreatic tumors, diabetes, or other metabolic or endocrine disorders. Always discuss results with your doctor for personalized guidance.

Short name

Glucagon Level

Frequently asked questions

What causes glucagon levels to be tested?
Glucagon testing is often done when symptoms like frequent hunger, unexplained weight changes, or blood sugar fluctuations don’t match typical diabetes or hypoglycemia patterns. It may also be part of a broader evaluation for suspected pancreatic or metabolic disorders.
How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab’s processing times. Your doctor will contact you once they have the findings.
Can I eat or drink before this test?
Follow your doctor’s instructions—some tests require fasting, while others allow light snacks. Always check with your provider before consuming anything before the procedure.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy