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Glucagon, Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucagon, a hormone produced by your pancreas, in your blood. Glucagon helps regulate blood sugar levels by signaling your liver to release glucose.

Quick summary

["Glucagon helps control how your body uses sugar for energy and can be checked if you have symptoms of low blood sugar or certain metabolic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
65344-4
Short code
Glucagon pre chal SerPl-mCnc
Synonyms
Glucagon pre chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like dizziness, confusion, or unexplained low blood sugar (hypoglycemia), especially if you have diabetes or other conditions affecting blood sugar. It may also be used to diagnose or monitor conditions like Zollinger-Ellison syndrome or other pancreatic or gastrointestinal disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the test if it’s part of a broader metabolic evaluation. Bring any medications you’re currently taking to your appointment.

How the Test Is Performed

A blood sample will be drawn from a vein in your arm by a healthcare professional. The blood is then sent to a lab for analysis using a sensitive measurement technique to detect glucagon levels.

What the Results Mean

Results are compared to standard reference ranges for glucagon concentration in serum. Abnormal levels may indicate conditions affecting hormone production, metabolism, or blood sugar regulation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High glucagon levels may suggest conditions like Zollinger-Ellison syndrome (a rare tumor causing excessive stomach acid) or other pancreatic or endocrine disorders. Low levels could be associated with certain metabolic or genetic conditions. Always discuss results with your provider for personalized interpretation.

Short name

Glucagon Level

Frequently asked questions

What causes glucagon levels to be checked?
Glucagon levels may be checked if you have symptoms like unexplained low blood sugar, digestive issues, or if your provider suspects a hormonal imbalance related to the pancreas or metabolism.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your provider will contact you once they have the results.
Can I take my medications before the test?
Yes, but always inform your healthcare provider about all medications you’re taking, including over-the-counter drugs or supplements, as they may affect test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy