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Glucagon, Serum (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucagon, a hormone produced by the pancreas, in your blood. Glucagon helps regulate blood sugar levels by signaling the liver to release glucose.

Quick summary

["Glucagon helps control how your body uses and stores sugar, and low or high levels may indicate certain health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
65345-1
Short code
Glucagon sp1 p chal SerPl-mCnc
Synonyms
Glucagon sp1 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained low blood sugar (hypoglycemia), unusual weight changes, or if they suspect a condition affecting hormone regulation, such as diabetes, pancreatic tumors, or other metabolic disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the test, depending on your doctor’s instructions. Bring any medications you’re taking, as they could affect results.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a needle. You may feel a small pinch when the needle goes in, but the procedure usually takes less than five minutes.

What the Results Mean

Results are interpreted by your healthcare provider based on your symptoms, medical history, and other test results. Abnormal levels may signal conditions like hypoglycemia, pancreatic disorders, or other metabolic issues that require further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucagon levels can be important in diagnosing or monitoring conditions like hypoglycemia (low blood sugar), pancreatic tumors, or rare metabolic disorders. High levels might suggest overproduction of glucagon, while low levels could indicate insufficient hormone function or other pancreatic issues.

Short name

Glucagon Level

Frequently asked questions

What causes glucagon levels to be tested?
Glucagon testing is often done if you have symptoms like unexplained weight loss, frequent hypoglycemia, or if your doctor suspects a hormonal imbalance or pancreatic problem.
How long does it take to get results?
Results are typically available within a few days to a week, depending on your lab’s processing time and your healthcare provider’s follow-up plan.
Can I eat or drink before this test?
Follow your doctor’s instructions, but fasting may be required for some patients. Always check with your provider before consuming anything.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy