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Glucagon concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucagon, a hormone produced by the pancreas, in your blood. Glucagon helps regulate blood sugar levels by signaling the liver to release glucose.

Quick summary

["Helps diagnose conditions affecting blood sugar control or pancreatic function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
65349-3
Short code
Glucagon sp5 p chal SerPl-mCnc
Synonyms
Glucagon sp5 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a glucagon test to check for conditions like hypoglycemia (low blood sugar), diabetes-related complications, or pancreatic disorders. It may also be used to evaluate how your body responds to glucagon in certain medical situations.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the test if it’s part of a glucose tolerance test. Avoid smoking or caffeine 30 minutes before the draw.

During the Test

A healthcare provider will insert a small needle into your arm to draw blood. You may feel a brief pinch, but the process is quick. The blood sample is sent to a lab for analysis.

After the Test

You can resume normal activities immediately. Apply gentle pressure to the injection site to stop any bleeding and monitor for signs of infection (e.g., redness, swelling). Report any severe discomfort or unusual symptoms to your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormally high glucagon levels may suggest conditions like pancreatic tumors, chronic pancreatitis, or certain metabolic disorders. Low levels could indicate severe liver disease, malnutrition, or other pancreatic issues. Glucagon testing is also used in research or specialized procedures to assess hormone function.

Short name

Glucagon Level

Frequently asked questions

When might I need this test?
If you have symptoms like unexplained low blood sugar, unexplained weight loss, or symptoms of pancreatic problems (e.g., abdominal pain), your doctor may recommend this test.
How long will results take?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
Can I eat or drink before this test?
Check with your doctor or lab for specific instructions, but fasting may be required if this test is part of a glucose-related study.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy