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Glucagon, Serum (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This blood test measures the amount of glucagon, a hormone produced by special cells in your pancreas. Glucagon helps regulate blood sugar levels by prompting your liver to release glucose.

Quick summary

["Glucagon helps control how your body uses sugar, so levels can indicate issues with blood sugar management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100816-8
Short code
Glucagon sp6 p chal SerPl-mCnc
Synonyms
Glucagon sp6 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like low blood sugar (hypoglycemia), unexplained weight loss, or signs of a rare condition called multiple endocrine neoplasia type 1 (MEN1). It could also be part of an evaluation for pancreatic disorders or metabolic diseases.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the draw if your doctor specifies it. Bring your test results or any medications you’re taking to your appointment.

What the Results Mean

Results are interpreted by your healthcare provider based on your symptoms and medical history. Elevated levels might suggest pancreatic tumors or other endocrine issues, while very low levels could indicate rare genetic disorders.

Common Conditions Linked to Abnormal Results

High glucagon levels may be associated with pancreatic tumors, diabetes complications, or certain metabolic syndromes. Low levels are less common but could relate to genetic disorders affecting hormone production.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucagon blood tests are primarily used to diagnose or monitor conditions affecting pancreatic function or hormone regulation. They’re not typically part of routine screening but may be included in specialized evaluations for suspected endocrine or metabolic disorders.

Short name

Glucagon Level

Frequently asked questions

Why might my glucagon test be ordered if I don’t have obvious symptoms?
Your doctor may order it as part of a broader evaluation for conditions like MEN1, unexplained weight changes, or if they suspect a pancreatic tumor. It’s also used in research or specialized cases where glucagon plays a key role in diagnosis.
Can fasting affect my glucagon test results?
Yes, fasting can influence glucagon levels. If fasting is required, follow your doctor’s instructions carefully, as glucagon naturally rises when blood sugar drops during fasting.
What should I do if my glucagon test results are outside the expected range?
Contact your healthcare provider immediately to discuss next steps. Abnormal results may require further testing, imaging, or a referral to an endocrinologist or specialist for evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy