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Glucose, Serum (High-Performance Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your blood drawn from a vein in your arm, using a specialized chromatography method.

Quick summary

["Helps monitor blood sugar levels for conditions like diabetes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12645-8
Short code
Glucose 10h p chal SerPl-mCnc
Synonyms
Glucose 10h p chal SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to check for high or low blood sugar levels. Common reasons include diagnosing diabetes, managing existing diabetes, or evaluating symptoms like excessive thirst, frequent urination, or unexplained weight changes.

What to Expect Before the Test

No special preparation is needed. You may be asked to fast for 8–12 hours before the test if it’s part of a fasting blood sugar panel, but this test alone does not require fasting.

During the Test

A healthcare provider will insert a small needle into your arm to draw blood. You may feel a slight pinch, but it usually takes only a few seconds. The blood sample is then sent to a lab for analysis using high-performance liquid chromatography to measure glucose concentration.

After the Test

You can resume normal activities immediately. There may be a small bruise or redness at the injection site, but this typically fades within a day or two. If you experience excessive bleeding or pain, contact your doctor.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose levels outside normal ranges can indicate diabetes, hypoglycemia (low blood sugar), or other metabolic conditions. Elevated levels may signal insulin resistance or undiagnosed diabetes, while persistently low levels can cause fatigue, dizziness, or confusion. Regular monitoring helps manage these conditions effectively.

Short name

Serum Glucose

Frequently asked questions

How long does it take to get results?
Results are usually available within 1–2 business days, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
Can fasting affect this test?
If this test is part of a fasting glucose panel, fasting is required to get an accurate measurement. If it’s a standalone test, fasting is not necessary, but your doctor may still recommend it for comparison with other tests.
What are common symptoms if my glucose is high or low?
High glucose levels may cause frequent urination, excessive thirst, blurred vision, or fatigue. Low glucose (hypoglycemia) can lead to shakiness, sweating, confusion, or weakness. If you experience severe symptoms, seek medical attention immediately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy