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Glucose, Plasma (High-Performance Liquid Chromatography Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) present in your blood plasma. It helps monitor blood sugar levels, often used in diabetes management or to assess metabolic health.

Quick summary

["This test helps track blood sugar levels for conditions like diabetes or metabolic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
1494-4
Short code
Glucose 1.5h p 100 g Glc PO SerPl-mCnc
Synonyms
Glucose 1.5h p 100 g Glc PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for diabetes, monitor blood sugar control in people with diabetes, evaluate metabolic disorders, or assess how your body processes glucose. It can also be used in research or specialized clinical settings to measure glucose concentration in plasma samples.

How Is the Sample Collected?

A small amount of blood is drawn from a vein, usually in your arm, and sent to a lab. The blood is processed to separate plasma, which is then tested for glucose levels using high-performance liquid chromatography (HPLC).

What Does the Result Mean?

The result provides the concentration of glucose in your plasma. While reference ranges vary by lab and method, this test helps determine if your blood sugar is within normal limits or if further action is needed.

Common Reasons for Abnormal Results

High glucose levels may indicate diabetes, poor blood sugar control, or other metabolic issues. Low levels could suggest hypoglycemia or certain medical conditions. Your doctor will discuss results in the context of your overall health.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose in plasma is a critical marker for diagnosing and managing diabetes, metabolic syndrome, and other conditions affecting blood sugar regulation. It helps doctors track how well treatments are working and identify risks for complications like nerve damage or heart disease.

Short name

Plasma Glucose

Frequently asked questions

How often should I expect this test?
Frequency depends on your medical condition. People without diabetes may get this test occasionally for routine checks, while those with diabetes often have it tested regularly (e.g., every few months) to monitor progress.
What can affect my test results?
Factors like recent meals, exercise, stress, medications (e.g., diabetes drugs), or certain foods (e.g., high-carb snacks) can influence glucose levels. Avoid eating or drinking anything except water for a specified period before testing if instructed.
Do I need to prepare for this test?
Preparation may vary. Typically, you might fast for 8–12 hours before the test, but always follow your doctor’s specific instructions to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy