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Glucose, Plasma (24-hour profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood sugar levels over a 24-hour period using plasma samples, helping assess how your body manages glucose throughout the day.

Quick summary

["This test helps doctors understand how your body handles blood sugar, especially if you have or are at risk for diabetes or other metabolic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11142-7
Short code
Glucose 15M p 100 g Glc PO SerPl-mCnc
Synonyms
Glucose 15M p 100 g Glc PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

A 24-hour glucose profile is often recommended for people with suspected diabetes, insulin resistance, or unexplained blood sugar fluctuations. It provides a detailed picture of how your body processes glucose, which can help identify patterns like reactive hypoglycemia or impaired glucose tolerance that standard single-point measurements might miss.

What to Expect Before the Test

You’ll typically fast overnight before collecting samples, with blood drawn at regular intervals (e.g., every 2–4 hours) over 24 hours. Follow your doctor’s instructions carefully to ensure accurate results. You may need to wear a special monitor or use a continuous glucose sensor to track levels at home.

How the Results Are Used

Your doctor will analyze the full profile to identify trends, such as peaks or drops in blood sugar, which can guide treatment decisions. For example, if levels spike after meals, your doctor may adjust medications or lifestyle recommendations.

Common Conditions Monitored

This test is particularly useful for diagnosing or managing diabetes (including type 1 and type 2), prediabetes, reactive hypoglycemia, or conditions like Cushing’s syndrome or pancreatic issues that affect glucose metabolism.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

None

Frequently asked questions

What does a high blood sugar reading mean?
High readings may indicate diabetes, insulin resistance, or other metabolic disorders. Your doctor will interpret results in context with your symptoms, other tests, and medical history to determine next steps, such as adjusting medications or diet.
What does a low blood sugar reading mean?
Low readings (hypoglycemia) can occur with certain medications, excessive alcohol use, or conditions like reactive hypoglycemia. If you experience symptoms like shakiness, dizziness, or confusion, report them to your doctor immediately.
How often should I get this test?
Your doctor will determine the frequency based on your health status, treatment plan, and risk factors. Regular follow-ups may be recommended if you have diabetes, prediabetes, or other chronic conditions affecting glucose control.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy