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Glucose, Serum (High-Pressure Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your blood drawn from a vein in your arm. It helps doctors check how well your body is using sugar for energy.

Quick summary

["This test helps monitor blood sugar levels, often used in diabetes management or during pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14754-6
Short code
Glucose 1h p 50 g Glc PO SerPl-sCnc
Synonyms
Glucose 1h p 50 g Glc PO SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to diagnose or manage conditions like diabetes, check for low blood sugar (hypoglycemia), or assess how your body processes glucose during pregnancy or illness. It can also help evaluate metabolic health or monitor treatment responses.

What to Expect Before the Test

You may be asked to fast for 8–12 hours before the test (if fasting is required), but your provider will confirm. Bring any medications you’re taking, as some may affect results. Avoid smoking or chewing gum right before the draw, as it can temporarily alter blood sugar levels.

During the Test

A small needle will be inserted into your arm to draw blood. You may feel a slight pinch, but it usually takes only a few seconds. The blood sample is then sent to a lab for glucose measurement using high-performance liquid chromatography (HPLC), a precise method for accurate results.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL). While reference ranges vary by lab, high or low values may signal underlying health concerns that need further evaluation by your doctor.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose levels outside normal ranges can indicate diabetes (high levels), hypoglycemia (low levels), or other metabolic disorders. Chronic high glucose may damage blood vessels over time, increasing risks for heart disease, nerve damage, or kidney problems. Regular monitoring helps prevent complications and guides treatment adjustments.

Short name

Glucose Level

Frequently asked questions

How often should I get this test?
The frequency depends on your health status. If you have diabetes, your doctor may recommend testing every few months or more often during pregnancy, illness, or if you’re taking medications that affect blood sugar.
Can I eat or drink anything before this test?
If fasting is required, avoid food and liquids (except water) for the specified period. Always follow your provider’s instructions to ensure accurate results.
Does this test hurt?
The needle insertion is quick and may cause a brief sting or pinch. Most people feel minimal discomfort afterward. If you’re anxious about needles, let your provider know they may offer alternatives like a tourniquet or distraction techniques.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy