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24-Hour Urine Glucose Measurement (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose (sugar) excreted in your urine over a 24-hour period. It helps assess how well your body is managing glucose levels, which can be important for diagnosing or monitoring conditions like diabetes.

Quick summary

["This test helps track how your body handles sugar over time, useful for diabetes management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45297-9
Short code
Glucose 24h Dial fld-sCnc
Synonyms
Glucose 24h Dial fld-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of diabetes, such as frequent urination, excessive thirst, or unexplained weight loss. It may also be used to monitor long-term glucose control in people with diabetes or to check for conditions like kidney issues that can affect urine sugar levels.

How the Test Works

You’ll collect all your urine over a full 24-hour period, typically starting after you wake up and ending just before you wake up the next morning. The urine is then tested for glucose concentration. This method provides a broader picture of your glucose metabolism compared to a single blood or urine sample.

Sample Collection and Preparation

To prepare, empty your bladder before starting the collection. Use a clean container (like a pitcher) to collect all urine for the entire day. Keep the sample refrigerated if not tested immediately. Label the container with your name, date, and time the collection began.

What to Expect During the Test

There’s no special preparation needed beyond collecting urine over 24 hours. You’ll likely be instructed to drink enough fluids to maintain normal urine output but avoid sugary drinks or medications that could affect results. Your healthcare provider will review the results with you.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Glucose

Frequently asked questions

What does a high or low result mean?
A high result may mean your body isn’t controlling glucose well, which could be linked to diabetes or other conditions. A low result might not indicate an issue unless your doctor suspects a metabolic problem.
How often should I get this test?
Your doctor will determine how often you need this test based on your health needs. For people with diabetes, it may be done less frequently than blood glucose tests but still as part of routine monitoring.
Can diet or medications affect this test?
Yes, certain foods, drinks (like sugary beverages), or medications can influence urine glucose levels. Your doctor will provide specific instructions to avoid these factors during your test period.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy