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Glucose, Serum (High-Performance Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your blood drawn from a vein. It helps monitor blood sugar levels, often used in diabetes management or general metabolic health assessments.

Quick summary

["This test helps track how well your body manages blood sugar, especially if you have diabetes or other conditions affecting metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9375-7
Short code
Glucose 2.5h p 100 g Glc PO SerPl-mCnc
Synonyms
Glucose 2.5h p 100 g Glc PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Glucose is your body’s primary energy source. High or low levels can cause health problems, such as nerve damage, heart disease, or fatigue. This test helps doctors check if your blood sugar is within a healthy range.

What to Expect Before the Test

You may be asked to fast (not eat or drink) for 8–12 hours before the test, depending on your doctor’s instructions. Bring any medications you’re taking. The blood is drawn from a vein in your arm, similar to a routine blood draw.

What the Results Mean

Results show your glucose concentration in milligrams per deciliter (mg/dL). While reference ranges vary by lab, very high or very low levels may signal diabetes, hypoglycemia, or other metabolic issues that need further evaluation.

Common Causes of Abnormal Results

Factors like diet, exercise, stress, or certain medications can affect glucose levels. If your results are outside normal ranges, your doctor may recommend lifestyle changes, medication adjustments, or follow-up tests.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose testing is critical for diagnosing diabetes, assessing prediabetes, or monitoring long-term blood sugar control. Repeated tests help track trends and adjust treatment plans to prevent complications like nerve damage or kidney issues.

Short name

Glucose Level (HPLC)

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your health needs. For example, people with diabetes may test every 3–6 months, while others might need it less often.
What if my results are high?
High glucose could mean diabetes or insulin resistance. Your doctor may recommend dietary changes, exercise, or medications to help manage it. Follow their advice closely.
Can I eat or drink before this test?
Yes, but fasting is often required. Ask your doctor or lab about specific instructions, as some tests allow water without sugar, while others require full fasting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy