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Glucose in Serum or Plasma (Fasting)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your blood after you’ve fasted for at least 8 hours. It helps assess how well your body uses sugar for energy.

Quick summary

["A fasting blood glucose test checks your blood sugar levels to detect diabetes or prediabetes risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55381-8
Short code
Glucose 2.5h p 75 g Glc PO SerPl-sCnc
Synonyms
Glucose 2.5h p 75 g Glc PO SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your doctor may order this test to check for diabetes, high blood sugar, or other metabolic conditions. It’s also used to monitor treatment progress for people already diagnosed with diabetes or related disorders.

What to Expect Before the Test

You’ll need to fast (not eat or drink anything except water) for 8–12 hours before the test. Your blood will be drawn from a vein, usually in your arm. The process is quick and typically painless.

How the Test Works

A small sample of your blood is taken and sent to a lab. The lab uses an automated method (often enzymatic or electrochemical) to measure glucose levels in your serum or plasma.

What the Results Mean

Results are compared to general reference ranges, but your doctor will interpret them based on your medical history and other test results. Abnormally high or low levels may signal health concerns that need further evaluation.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High fasting glucose levels (above normal ranges) may indicate diabetes, insulin resistance, or prediabetes. Consistently low levels could signal hypoglycemia or other metabolic issues. Regular monitoring helps prevent long-term complications like nerve damage, kidney disease, or heart problems.

Short name

Fasting Blood Glucose

Frequently asked questions

What causes fasting blood glucose to be high?
Several factors can raise fasting blood glucose, including genetics, obesity, lack of physical activity, certain medications (like steroids), or chronic stress. Diabetes, polycystic ovary syndrome (in women), and some infections may also contribute.
Hypoglycemia (low blood sugar) can result from excessive insulin use (e.g., from diabetes medication), certain medications (like beta-blockers or insulin), alcohol consumption, or prolonged fasting. It may also occur in people with adrenal or pituitary disorders.
Your doctor will determine how often you need this test based on your health status. People without diabetes may get it once every 1–3 years as a routine check. Those with diabetes or prediabetes may need it more frequently (e.g., every 1–2 years or annually).
Can I eat or drink anything before the test?
No, you must fast for 8–12 hours before the test. Only water is allowed. Avoid alcohol, caffeine, or sugary drinks during this time to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy