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Glucose measured in plasma (24-hour profile)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates your blood sugar levels over a full day, helping track how your body manages glucose throughout your routine.

Quick summary

["Understanding your glucose levels over time can help manage diabetes or metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40037-4
Short code
Glucose 25h p chal SerPl-mCnc
Synonyms
Glucose 25h p chal SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

A 24-hour glucose profile is often recommended for people with diabetes to assess how their body responds to food, activity, and medications over time. It may also be used to evaluate prediabetes or to monitor metabolic conditions like hypoglycemia or insulin resistance.

What to Expect Before the Test

You’ll typically fast overnight before this test. Your healthcare provider may give specific instructions, such as avoiding certain foods or medications. A healthcare professional will collect blood samples from a vein in your arm at set intervals throughout the day.

What the Test Measures

This test measures the concentration of glucose (sugar) in your plasma over 24 hours. The results help identify patterns in your blood sugar levels, such as spikes after meals or low points during certain times of the day.

How Results Are Interpreted

Results are analyzed to compare your glucose levels against expected ranges for healthy individuals or those with diabetes. Patterns like repeated high or low readings may indicate issues with insulin function, diet, or medication.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A 24-hour glucose profile provides a comprehensive view of how your body processes glucose, which is critical for diagnosing diabetes, assessing treatment effectiveness, or identifying metabolic disorders. It helps healthcare providers tailor diabetes management plans, including diet, exercise, and medication adjustments.

Short name

Glucose Profile (Plasma, 24-Hour)

Frequently asked questions

How often should I expect this test?
This test is usually done once or twice a year for people with diabetes, depending on their treatment plan. Your doctor may recommend it more frequently if you have unstable blood sugar levels or if you’re adjusting medications.
What does a normal glucose profile look like?
A normal glucose profile shows consistent blood sugar levels without extreme spikes or drops. For people with diabetes, results help determine if their current treatment keeps glucose within safe ranges, but exact patterns depend on individual health and treatment.
Can I eat or drink anything before the test?
You’ll need to fast for 8–12 hours before the test, but your doctor will give exact instructions. Avoid alcohol and certain medications as directed, as they can affect results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy