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Glucose, 24-Hour Urine Collection (Total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose excreted in your urine over a 24-hour period, often used to assess how well your body manages glucose levels.

Quick summary

["Helps identify if your body is handling glucose properly, especially in conditions like diabetes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40214-9
Short code
Glucose 25h p chal SerPl-sCnc
Synonyms
Glucose 25h p chal SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

A 24-hour urine collection for glucose is typically ordered to evaluate how much glucose appears in your urine. This can help doctors diagnose or monitor conditions like diabetes, where glucose might spill into urine due to high blood sugar levels or kidney issues. It may also be used to check for other metabolic disorders or to assess response to treatments.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, starting right after you wake up and ending just before you wake up the next day. Drink plenty of fluids to help flush out glucose, but avoid sugary drinks or foods. Store the urine in a clean container and keep it refrigerated until you return it to the lab.

What Happens During the Test

No special preparation is needed beyond the urine collection. The lab will analyze the total glucose content in your urine sample to determine if it exceeds normal levels.

What the Results Mean

Results are compared to expected values for a healthy individual. Elevated levels may indicate diabetes, kidney problems, or other metabolic conditions. Your doctor will discuss the results in the context of your overall health and symptoms.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High urine glucose levels can signal diabetes or impaired kidney function, as the kidneys may not filter glucose properly. It can also help detect undiagnosed diabetes or monitor treatment effectiveness. Low or absent glucose in urine may suggest normal glucose metabolism or conditions like severe dehydration.

Short name

Urine Glucose Profile

Frequently asked questions

What causes glucose to appear in urine?
Glucose in urine (glycosuria) can occur when blood sugar levels are consistently high, such as in diabetes, or when the kidneys are unable to reabsorb glucose effectively. Stress, illness, or certain medications may also temporarily increase urine glucose levels.
Is there any risk or discomfort with this test?
No, there’s no discomfort. The main effort is collecting urine over 24 hours, which requires careful timing and storage. If you have difficulty collecting urine, your doctor may suggest alternative tests.
How often is this test recommended?
This test is typically recommended for people with diabetes, those at high risk for diabetes, or those with symptoms like frequent urination, excessive thirst, or unexplained weight changes. Your doctor may also order it periodically to monitor your condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy