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Glucose and Fructosamine Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood sugar (glucose) level and a protein-related marker (fructosamine) that reflects how your blood sugar has been controlled over the past two weeks.

Quick summary

["Helps track blood sugar trends and diabetes management over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51766-4
Short code
Glucose 2.5h p fructose PO SerPl-mCnc
Synonyms
Glucose 2.5h p fructose PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Blood Sugar Control

Glucose levels provide a snapshot of your current blood sugar, while fructosamine gives insight into how consistently your blood sugar has been managed. Together, they help doctors assess both short-term and longer-term diabetes control.

What Each Measurement Tells You

• **Glucose** – Shows your immediate blood sugar level, which can spike or drop depending on meals, activity, or medications. • **Fructosamine** – Reflects average blood sugar over the past 2–3 weeks by measuring glycated proteins, helping identify trends in glucose management.

When This Test Is Ordered

Doctors may order this test if you have diabetes to monitor long-term glucose control, evaluate treatment effectiveness, or check for complications like poor glucose regulation. It’s also used in research or specialized care plans.

What to Expect Before the Test

No special preparation is needed unless instructed. You may have a blood draw from a vein (like an arm) or a fingerstick for glucose. Fructosamine is typically measured in serum or plasma, so fasting isn’t required but may be recommended for glucose alone.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Beyond Just Blood Sugar Numbers

Short name

Glucose & Fructosamine Test

Frequently asked questions

Why might my glucose and fructosamine levels be checked together?
Glucose alone can be misleading—it only reflects your blood sugar at the moment of testing. Fructosamine complements it by showing how your blood sugar has influenced proteins in your body over time. Together, they help detect patterns like poor control, recent spikes, or treatment adjustments needed.
Can fructosamine replace HbA1c?
No, they serve different purposes. Fructosamine gives a shorter-term (2–3 weeks) view of glucose control, while HbA1c (hemoglobin A1c) measures average glucose over 2–3 months. This test combines glucose with fructosamine for a hybrid approach.
What if my glucose is high but fructosamine is normal?
This could mean your blood sugar was consistently normal recently but spiked recently (e.g., due to illness, stress, or missed insulin). Your doctor may adjust monitoring or treatment based on these results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy