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Glucose, 24-Hour Urinary Collection (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose (sugar) excreted in your urine over a 24-hour period. It helps assess how well your body is managing glucose levels, especially important for people with diabetes or kidney function concerns.

Quick summary

["This test helps track urinary sugar loss, which can indicate diabetes or kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40040-8
Short code
Glucose 28h p chal SerPl-mCnc
Synonyms
Glucose 28h p chal SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like frequent urination, excessive thirst, or unexplained weight changes. It’s also used to monitor diabetes management or kidney function, particularly in people with high blood sugar or kidney disease.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours, starting and ending with your first morning urine. Store the sample at room temperature and bring the entire collection to the lab. Follow any specific instructions your provider gives to ensure accurate results.

How the Test Works

The test measures the total glucose present in your urine over the day. Your sample is analyzed using a specialized method (likely enzymatic or chromatographic) to determine the mass concentration of glucose.

What the Results Mean

Results are typically reported as the total amount of glucose excreted in grams or milligrams over 24 hours. High levels may suggest diabetes, poor kidney function, or other metabolic conditions. Low levels might indicate dehydration or restricted glucose intake.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated urinary glucose can signal diabetes (type 1 or 2), kidney problems, or conditions like gestational diabetes. Persistently high levels may require adjustments to diabetes management, such as medication or diet. Low results could raise concerns about dehydration or inadequate glucose metabolism, prompting further evaluation.

Short name

None

Frequently asked questions

What causes abnormal urinary glucose levels?
Abnormal urinary glucose can result from diabetes (high blood sugar), kidney disease (which may impair glucose reabsorption), or conditions like gestational diabetes. Other factors, such as certain medications or infections, may also play a role.
How often should I get this test?
Your provider will determine the frequency based on your health needs. For people with diabetes, it may be done annually or more often if blood sugar or kidney function is unstable. Follow-up testing depends on your treatment plan and symptoms.
Can diet or activity affect this test result?
Yes. High-carb diets or intense physical activity can temporarily increase urinary glucose. Avoiding sugary foods or drinks for 24 hours before testing may help stabilize results. Your provider will give specific guidance tailored to your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy