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Glucose, 24-Hour Urinary Excretion (Total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose (sugar) excreted in your urine over a 24-hour period. It helps assess how well your body is handling glucose metabolism, often linked to conditions like diabetes.

Quick summary

["This test helps doctors evaluate long-term glucose control and identify urinary glucose loss, which may signal diabetes or other metabolic issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40045-7
Short code
Glucose 2D p chal SerPl-mCnc
Synonyms
Glucose 2D p chal SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if they suspect you have diabetes or prediabetes, or if you experience symptoms like frequent urination, excessive thirst, or unexplained weight changes. It can also help monitor kidney function or check for conditions like glycosuria (glucose in urine) that may not be detected by blood tests alone.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, typically starting after you urinate in the morning of day one. Store the urine in a clean container, keeping it refrigerated if possible. Bring all collected urine to your lab appointment.

How the Test Works

The test measures the total glucose present in your urine over the 24-hour period. The lab analyzes the combined sample to determine the amount of glucose excreted, which reflects how much glucose your body is processing and eliminating.

What the Results Mean

Results are interpreted based on the total glucose excreted, not individual measurements. High levels may indicate diabetes or other metabolic disorders, while normal results suggest your body handles glucose efficiently. Your doctor will discuss these results with you in context of your health.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated urinary glucose can signal diabetes, where the body struggles to regulate blood sugar properly. It may also indicate kidney issues or other metabolic conditions. Regular monitoring helps manage these conditions and prevent complications like nerve damage or kidney disease.

Short name

24-Hour Urine Glucose

Frequently asked questions

How is this test different from a standard blood glucose test?
This test measures glucose lost in urine over 24 hours, giving a broader picture of how your body processes sugar. A standard blood test checks current blood sugar levels, while this test helps assess long-term urinary glucose excretion, which can be important for diagnosing or monitoring diabetes-related urinary issues.
What causes high urinary glucose levels?
High urinary glucose is most commonly linked to diabetes, where the body either doesn’t produce enough insulin or can’t use it properly. Other causes may include kidney problems, certain medications, or hormonal imbalances.
Can I drink fluids before or during the 24-hour urine collection?
Yes, you can drink fluids as usual unless your doctor specifies otherwise. However, avoid alcohol or caffeine in excess, as they may affect urine composition and test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy