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Glucose, Plasma (High-Performance Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your plasma, the liquid part of blood that carries nutrients and waste products to and from cells.

Quick summary

["Your doctor may use this test to check blood sugar levels, monitor diabetes, or assess metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11143-5
Short code
Glucose 45M p 100 g Glc PO SerPl-mCnc
Synonyms
Glucose 45M p 100 g Glc PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors order plasma glucose tests to diagnose conditions like diabetes, track blood sugar trends, or evaluate how your body processes glucose. It may also be used during pregnancy, before surgeries, or to monitor chronic illnesses affecting metabolism.

How Is the Test Performed?

A healthcare provider will draw blood from a vein in your arm using a small needle. The blood sample is collected in a tube and sent to a lab for analysis using high-performance liquid chromatography (HPLC), a precise method to measure glucose concentration.

What Should You Expect Before or After the Test?

No special preparation is needed unless instructed by your doctor. You may feel slight discomfort during the blood draw, but it usually resolves quickly. Avoid eating or drinking for a specified period (if required) to ensure accurate results.

What Are Common Results and Their Meanings?

Results are typically reported in milligrams per deciliter (mg/dL). Lower or higher-than-expected values may signal underlying health concerns, such as hypoglycemia or hyperglycemia, and should be discussed with your provider.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Plasma glucose levels are critical for diagnosing diabetes, assessing insulin resistance, and monitoring metabolic disorders. Abnormal results may indicate poor blood sugar control, prediabetes, or other metabolic syndromes. Regular monitoring helps prevent long-term complications like nerve damage or heart disease.

Short name

Plasma Glucose

Frequently asked questions

How often should I expect this test?
The frequency depends on your health status. If you have diabetes, your doctor may recommend testing every few months or more often to track trends. Others may only need it once or as part of routine check-ups.
What if my results are outside the normal range?
If your results are abnormal, your doctor will review them with you and may recommend further testing or lifestyle changes, such as diet, exercise, or medication adjustments. Never interpret results independently—always consult your healthcare provider.
Does fasting affect this test?
Yes, fasting (not eating or drinking except water) for 8–12 hours before the test is often required to get an accurate fasting glucose measurement. If you have questions, ask your doctor about specific instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy