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Glucose, Serum (High-Performance Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose, a type of sugar, in your blood serum. It helps assess how well your body is managing blood sugar levels.

Quick summary

["This test checks your blood sugar, which is important for managing diabetes and other metabolic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48810-6
Short code
Glucose 5h p 50 g Glu PO SerPl-mCnc
Synonyms
Glucose 5h p 50 g Glu PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors order glucose tests to monitor blood sugar levels, diagnose diabetes or prediabetes, or check for conditions like hypoglycemia (low blood sugar). It may also be used during pregnancy to screen for gestational diabetes or before certain surgeries.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. If fasting is required (e.g., for certain glucose tests), follow your healthcare provider’s instructions about diet and activity.

What the Test Results Mean

Results are typically reported in milligrams per deciliter (mg/dL). While reference ranges vary by lab, high or low values can signal diabetes, insulin resistance, or other health concerns. Your doctor will interpret results in the context of your overall health.

Common Conditions Linked to Glucose Levels

Abnormally high or low glucose levels can indicate diabetes, hypoglycemia, kidney disease, or hormonal imbalances. Repeated testing may be needed to track trends over time.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose tests are critical for diagnosing and managing diabetes, preventing complications like nerve damage or heart disease, and ensuring proper treatment adjustments. They also help identify risks for conditions like heart disease or stroke.

Short name

Glucose Level (Serum)

Frequently asked questions

What causes blood sugar levels to be tested?
Blood sugar tests are often done if you have symptoms like excessive thirst, frequent urination, fatigue, or unexplained weight changes. They may also be part of routine check-ups, especially for people at higher risk of diabetes.
How often should I get a glucose test?
Frequency depends on your health status. People with diabetes usually get tests every few months, while others may need them less often. Your doctor will recommend a schedule based on your needs.
Can lifestyle changes affect glucose test results?
Yes! Diet, exercise, and stress can impact blood sugar levels. If you’re preparing for a test, avoid eating or drinking (except water) for 8–12 hours beforehand, unless instructed otherwise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy