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Glucose, Plasma (High-Performance Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your plasma, a liquid part of blood that carries nutrients and waste products.

Quick summary

["It helps monitor blood sugar levels, often used in diabetes management or during medical evaluations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
1542-0
Short code
Glucose 5h p 75 g Glc PO SerPl-mCnc
Synonyms
Glucose 5h p 75 g Glc PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like diabetes, monitor blood sugar trends, or assess metabolic health. It can also help diagnose or manage other conditions affecting how your body uses glucose, such as liver or kidney disease.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate plasma, which is analyzed using high-performance liquid chromatography (HPLC) to measure glucose concentration accurately.

What Do Results Mean?

Results provide a snapshot of your glucose levels at the time of testing. While specific ranges vary by lab and clinical context, abnormal results may signal high or low blood sugar, prompting further evaluation.

Common Reasons for Testing

This test is frequently used in routine check-ups, diabetes care plans, or when symptoms like excessive thirst, fatigue, or unexplained weight changes are present.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Glucose Levels and Health

Short name

Plasma Glucose

Frequently asked questions

How often should I expect this test?
Frequency depends on your health status. People with diabetes may test more often (e.g., weekly or monthly) to track trends, while others may have it done less frequently, such as every few months or annually.
What if my glucose level is too high or too low?
High or low glucose levels can cause symptoms like dizziness, confusion, or nausea. If you experience these, report them to your provider immediately. They may adjust your treatment plan, such as medication or diet, based on results.
Can I eat or drink before this test?
Typically, fasting is required for accurate results, but follow your provider’s instructions. Some tests may allow for minimal food or fluids, so check with your lab or healthcare team beforehand.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy