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Glucose, Serum or Plasma (High-Performance Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your blood drawn from a vein or capillary. It helps assess how well your body is using sugar for energy.

Quick summary

["Glucose levels can indicate blood sugar control, potential diabetes, or metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40167-9
Short code
Glucose 7h p chal SerPl-sCnc
Synonyms
Glucose 7h p chal SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like diabetes, hypoglycemia (low blood sugar), or to monitor blood sugar levels during treatment for metabolic disorders. It can also help evaluate how your body responds to medications or dietary changes.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast (not eat) for 8–12 hours before the test if it’s part of a fasting glucose study. If drawn from a capillary (fingerstick), you might experience a small sting, but vein draws are less painful.

What Happens During the Test?

A healthcare professional will insert a small needle into a vein in your arm or take a small drop from your fingertip to collect a blood sample. The sample is then sent to a lab for analysis using high-performance liquid chromatography (HPLC), which separates and measures glucose accurately.

What Are the Results Meaning?

Results are typically reported in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). Your provider will compare these results to your individual reference ranges and clinical context to determine if further action is needed.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High glucose levels may signal diabetes, prediabetes, or other metabolic issues, while persistently low levels could indicate hypoglycemia or endocrine disorders. Regular monitoring helps manage blood sugar, prevent complications, and tailor treatment plans.

Short name

Glucose Level

Frequently asked questions

What causes abnormal glucose levels?
Abnormal glucose levels can result from conditions like diabetes (high glucose), untreated hypoglycemia (low glucose), stress, infections, or certain medications. Lifestyle factors such as diet, physical activity, or sleep also play a role.
How often should I get this test?
Frequency depends on your health status. People with diabetes may need testing every few months, while others may only need it once or twice a year. Your provider will recommend a schedule based on your needs.
Can diet or exercise affect test results?
Yes. Fasting before the test ensures accurate fasting glucose results. Eating or drinking (except water) can raise glucose levels. Exercise may temporarily lower glucose, so timing your test around activity can impact results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy