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8-Hour Oral Glucose Tolerance Test (8-hour Serum Glucose)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood sugar level 8 hours after drinking a sugary liquid. It helps assess how well your body manages glucose over time, often used to evaluate diabetes or prediabetes.

Quick summary

["This test helps doctors check long-term blood sugar control beyond just a single reading."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
21306-6
Short code
Glucose 8h Ur-mRate
Synonyms
Glucose 8h Ur-mRate
Category
glucose
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may recommend this test if you have symptoms of diabetes (like frequent urination, extreme thirst, or unexplained weight changes) or if you have risk factors such as obesity, high blood pressure, or a family history of diabetes. It’s also used to monitor glucose levels in people with known diabetes to ensure proper management.

How the Test Works

You’ll drink a sugary liquid (usually glucose solution) while fasting. Blood is drawn from a vein in your arm at baseline and then again 8 hours later to measure your glucose level. This helps determine how your body processes glucose over an extended period.

Sample Collection

A healthcare provider will insert a small needle into your arm to collect blood. You may feel a slight pinch, but it’s usually over quickly. The blood is sent to a lab for testing.

What to Expect Before the Test

You’ll need to fast (not eat or drink anything except water) for about 12 hours before the test. Avoid caffeine, alcohol, and smoking on the day of the test. Let your doctor know about any medications you’re taking, as some may affect results.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: urine

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

8-hour glucose

Frequently asked questions

What does an abnormal result mean?
An elevated result may mean your body struggles to regulate blood sugar properly, which could signal prediabetes or diabetes. Your doctor will discuss next steps, such as lifestyle changes, medication, or further testing.
Can I eat or drink anything before the test?
No, you must fast for 12 hours before the test, only drinking water. Avoid food, beverages (except water), caffeine, alcohol, or smoking.
How long will I need to prepare for this test?
Preparation typically involves fasting for about 12 hours before the test, so plan accordingly. Your doctor may provide specific instructions based on your health status.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy