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Glucose, Plasma (High-Performance Liquid Chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) present in your plasma, a component of blood.

Quick summary

["Plasma glucose levels help assess blood sugar control and identify potential diabetes or metabolic issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12644-1
Short code
Glucose 9h p chal SerPl-mCnc
Synonyms
Glucose 9h p chal SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like diabetes, monitor blood sugar levels, or evaluate how your body processes glucose. It’s often used alongside other tests to diagnose or manage metabolic disorders.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a fasting glucose profile. Bring any medications you’re currently taking.

How the Test Works

A small blood sample is drawn from a vein in your arm. The plasma portion is separated and analyzed using high-performance liquid chromatography (HPLC) to measure glucose concentration accurately.

What the Results Mean

Results help determine if your blood sugar is within normal ranges or if further action is needed. Abnormal results may prompt additional testing or lifestyle adjustments.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Glucose Levels and Health

Short name

Plasma Glucose

Frequently asked questions

How often should I get this test?
The frequency depends on your health status. People with diabetes typically check plasma glucose regularly, while others may get it less often—usually as recommended by their doctor.
Can I eat or drink before this test?
If fasting is required, avoid food and liquids (except water) for the specified time. If fasting isn’t needed, you can eat and drink normally, but check with your provider first.
What if my results are high or low?
High or low results may signal diabetes, hypoglycemia, or other metabolic issues. Your doctor will discuss next steps, which could include diet changes, medication, or further testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy