Skip to content

24-Hour Urine Collection for Glucose and Creatinine Ratio (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of glucose and creatinine in your urine over 24 hours to assess how well your kidneys filter glucose. It helps detect conditions like diabetes or kidney-related glucose issues.

Quick summary

["Checks kidney function and glucose handling in urine over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99602-5
Short code
Glucose/Creat 24h Ur-sRto
Synonyms
Glucose/Creat 24h Ur-sRto
Category
glucose
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if they suspect you have diabetes, kidney problems, or other metabolic conditions affecting how your body processes glucose. It helps track how much glucose appears in your urine, which can indicate how well your kidneys are working to remove it.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours, starting after midnight on one day and ending after midnight the next. Follow your doctor’s instructions carefully to ensure accurate results. You may need to wear a collection bag or use a container to store your urine samples.

How the Test Works

Your urine is tested for both glucose and creatinine levels. Creatinine is a waste product naturally present in your blood, and its levels help normalize glucose measurements. The ratio helps identify patterns in glucose excretion that may not be visible in a single blood test.

Possible Results and Interpretation

Results are typically expressed as a ratio rather than absolute values. High ratios may suggest diabetes or kidney issues, while normal ratios indicate typical glucose handling. Your doctor will interpret results based on your medical history and symptoms.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: urine

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Glucose-to-Creatinine Urine Ratio (24-hour)

Frequently asked questions

What Does This Test Measure?
This test measures the ratio of glucose to creatinine in urine over 24 hours. Glucose appears in urine when your kidneys are unable to reabsorb it properly, often due to diabetes or kidney dysfunction. Creatinine helps standardize the measurement by accounting for urine concentration.
How Might This Test Help My Doctor?
Your doctor may use this test to diagnose or monitor diabetes, kidney disease, or other metabolic disorders. It provides a broader picture of how your body processes glucose over time compared to a single blood test.
What Are Common Causes of Abnormal Results?
Abnormally high ratios may indicate diabetes, kidney disease, or conditions like gestational diabetes. Abnormally low ratios are less common but could suggest severe kidney dysfunction or other metabolic issues. Always discuss results with your healthcare provider.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy