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Glucose Creatinine Ratio (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of glucose in your blood serum to creatinine, a waste product from muscle metabolism. It helps assess how well your kidneys are filtering glucose from your blood.

Quick summary

["A useful tool to check kidney function and glucose control together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110522-0
Short code
Glucose/Creat Msmt Ur
Synonyms
Glucose/Creat Msmt Ur
Category
glucose
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like frequent urination, excessive thirst, or unexplained weight loss. It can also be used to monitor conditions like diabetes or kidney disease, especially in people with high blood sugar or kidney concerns. Some patients may also get it as part of routine screening or to evaluate kidney function in chronic illnesses.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a blood sample drawn from a vein, usually in your arm, similar to other blood tests. If you’re on dialysis or have a central venous catheter, your healthcare provider will explain how the sample will be taken.

What the Results Mean

The ratio compares glucose levels to creatinine, which stays relatively constant in the blood. Elevated glucose levels with normal creatinine might suggest diabetes or poor kidney function. Lower-than-expected glucose levels could indicate conditions like hypoglycemia or certain metabolic disorders. Your results will be interpreted by a healthcare provider based on your overall health and medical history.

Possible Causes of Abnormal Results

High glucose-to-creatinine ratios may indicate diabetes, kidney disease, or conditions that affect how your body processes glucose. Low ratios could be linked to hypoglycemia, certain liver or kidney disorders, or medications that lower blood sugar. Always discuss any abnormal results with your doctor to explore potential causes and next steps.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: urine

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Glucose-to-Creatinine Ratio

Frequently asked questions

How often do I need this test?
Your doctor will determine how often you need this test based on your medical history, symptoms, and overall health. For example, people with diabetes may need it more frequently to monitor glucose control, while others might get it less often as part of routine check-ups or if they have kidney-related conditions.
Can I eat or drink before the test?
You can eat and drink normally before this test unless your doctor instructs otherwise. Since it’s a blood test, fasting isn’t required, but check with your healthcare provider for any specific guidelines.
Will the test affect my medications?
This test itself won’t directly affect your medications, but your results may influence your doctor’s decisions about your treatment plan. If you’re on diabetes medications or other blood sugar–related treatments, let your doctor know before discussing results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy