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Glucose and Insulin Ratio (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the relationship between your blood glucose levels and insulin levels to help assess how your body responds to glucose.

Quick summary

["Helps evaluate insulin sensitivity and glucose metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
62418-9
Short code
Glucose/Insulin SerPl-Rto
Synonyms
Glucose/Insulin SerPl-Rto
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test evaluates the ratio of glucose (a type of sugar in your blood) to insulin (a hormone that helps regulate blood sugar). It provides insight into how effectively your body uses insulin to manage glucose levels.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms of insulin resistance, prediabetes, or diabetes, or if you’re at risk for metabolic disorders.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is processed to measure both glucose and insulin levels, then the ratio is calculated.

What Are the Results Used For?

Results help determine if your body is producing enough insulin to control blood sugar levels, which can guide treatment plans for conditions like insulin resistance or diabetes.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is particularly useful in diagnosing or monitoring insulin resistance, metabolic syndrome, or conditions affecting glucose metabolism. It may also be used in research or specialized clinical assessments.

Short name

Glucose-Insulin Ratio

Frequently asked questions

Why would my doctor ask for this test?
Your doctor might recommend it if you have symptoms like frequent hunger, fatigue, or unexplained weight changes, or if you have a family history of diabetes or metabolic disorders.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
Can I eat or drink before this test?
Yes, you can eat and drink normally, but fasting may not be required unless specified by your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy