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Glucose in Serum or Plasma (24-Hour Fluid Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your blood over a 24-hour period using a sample of your serum or plasma. It helps assess how well your body manages blood sugar levels throughout the day.

Quick summary

["Understanding your body’s natural glucose fluctuations can help identify patterns or conditions affecting blood sugar control."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109723-7
Short code
Glucose Msmt Dial fld
Synonyms
Glucose Msmt Dial fld
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent hunger, fatigue, or unexplained weight changes, or if you have conditions like diabetes, hypoglycemia, or metabolic disorders. It may also be used to monitor treatment effectiveness or diagnose glucose-related issues in certain populations.

How the Test Works

A sample of your blood (serum or plasma) is collected over 24 hours, often via a catheter or multiple draws. The glucose levels are measured at intervals to create a profile of your blood sugar activity. The test may also involve a fluid collection (e.g., urine or other bodily fluids) depending on clinical context.

What to Expect Before the Test

No special preparation is typically required unless instructed by your provider. You may need to follow a specific diet or activity restrictions, such as avoiding certain foods or medications, to ensure accurate results. Always follow your provider’s guidance.

What to Expect During the Test

Blood samples are drawn at scheduled intervals, often over a full day. You may experience mild discomfort at the insertion site, but most people tolerate the process well. If fluid collection is involved, follow your provider’s instructions for proper sample handling.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Glucose Profile

Frequently asked questions

How long does it take to get results?
Results are typically processed within a few days to a week, depending on lab capacity and your provider’s workflow. Follow-up with your healthcare provider to discuss the findings.
What does a normal glucose profile look like?
A normal profile shows consistent glucose levels without extreme spikes or drops. However, reference ranges vary by individual, and your provider will interpret the results in the context of your health and symptoms.
Can lifestyle changes affect this test?
Yes, diet, exercise, stress, and medications can influence glucose levels. If you’re undergoing this test, avoid major lifestyle changes unless directed by your provider to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy