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Glucose in Serum or Plasma (24-Hour Fluid Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) in your blood over a 24-hour period, typically collected from a fluid sample (serum or plasma).

Quick summary

["Understanding your blood sugar levels over time helps monitor diabetes or other metabolic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109417-6
Short code
Glucose Msmt Fld
Synonyms
Glucose Msmt Fld
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to assess how well your body regulates blood sugar, especially if you have diabetes, prediabetes, or other conditions affecting metabolism. It can also help diagnose or monitor conditions like hypoglycemia (low blood sugar) or track responses to treatments.

What to Expect Before the Test

You’ll need to collect a fluid sample (serum or plasma) over 24 hours, often at home, by measuring urine or blood glucose levels at scheduled intervals. Follow your provider’s instructions carefully to ensure accurate results.

What the Test Results Mean

The test provides an average glucose level over 24 hours, which can reveal patterns in blood sugar fluctuations. While reference ranges vary by lab, consistent high or low readings may indicate diabetes, insulin resistance, or other metabolic issues.

Common Conditions Monitored

This test is often used to diagnose or manage diabetes, including type 1 and type 2 diabetes, as well as conditions like reactive hypoglycemia or gestational diabetes.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose levels measured over time help identify whether your body is effectively managing sugar, which is critical for preventing long-term complications like nerve damage, kidney disease, or heart problems. Abnormal results may prompt further testing or adjustments to medication or lifestyle.

Frequently asked questions

What does a 24-hour glucose test measure?
It measures the average blood sugar level over a full day, typically using urine or blood samples collected at regular intervals to reflect daily fluctuations.
How is the fluid sample collected?
You’ll collect a fluid sample (serum/plasma or urine) at home, following your provider’s instructions, often by measuring glucose levels at set times throughout the day.
Can I eat or drink normally during the test?
Yes, but avoid alcohol or sugary foods/drinks that could affect results. Follow your provider’s specific guidelines for diet and timing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy