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Glucose in Serum (24-hour urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose (sugar) excreted in your urine over a 24-hour period. It helps assess how well your body is handling glucose and can identify conditions like diabetes or kidney issues.

Quick summary

["A 24-hour urine glucose test helps track sugar levels in your urine over time, useful for diabetes management or kidney function evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110643-4
Short code
Glucose Msmt Stl
Synonyms
Glucose Msmt Stl
Category
glucose
Sample
stool
Container
Clean container
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if they suspect diabetes, kidney problems, or other metabolic conditions. It can also help monitor how well medications are working to control blood sugar levels. Some people with kidney disease may also need this test to check for excessive glucose in urine, which can indicate kidney damage.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours, starting from one point in the morning (often the first morning urine is discarded). Store the urine in a clean container, keeping it refrigerated if possible. Follow your doctor’s instructions carefully to ensure accurate results.

How the Test Works

The collected urine is analyzed to measure the total glucose present. This is done using a specialized lab method to detect and quantify glucose in the sample, often through an immunoassay or enzymatic technique.

What the Results Mean

Higher than expected levels of glucose in urine can signal diabetes, kidney problems, or other metabolic disorders. Your doctor will interpret the results in relation to your overall health and medical history. Normal results may indicate your body is handling glucose well.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: stool

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Glucose in Urine Can Signal Underlying Health Issues

Short name

24-Hour Urine Glucose

Frequently asked questions

What causes elevated urine glucose?
Elevated urine glucose is most commonly linked to diabetes (both type 1 and type 2), where the body either doesn’t produce enough insulin or can’t use insulin properly. Kidney issues, such as nephrotic syndrome, can also cause glucose to appear in urine when it shouldn’t. Other conditions, like certain infections or hormonal imbalances, may also play a role.
How often should I get this test?
The frequency depends on your health status. People with diabetes typically get this test regularly (sometimes monthly) to monitor glucose control. Others with kidney disease or suspected metabolic disorders may need it less often, but your doctor will determine the best schedule for you.
Can I eat or drink anything before the test?
You can eat and drink normally, but avoid sugary drinks or foods that might affect your urine glucose levels. Follow your doctor’s specific instructions to ensure accurate results, as some medications or dietary changes could impact the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy