Skip to content

Glucose and Fructose Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood levels of glucose (sugar) and fructose (a sugar alcohol), often checked together to assess metabolic health or detect unusual sugar metabolism.

Quick summary

["Understanding your blood sugar and fructose balance helps identify diabetes, metabolic disorders, or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48606-8
Short code
Glucose Pre fructose PO SerPl-mCnc
Synonyms
Glucose Pre fructose PO SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like frequent thirst, fatigue, or unexplained weight changes. It may also be used to monitor conditions like diabetes, fructose intolerance, or metabolic syndrome. Rarely, it could help diagnose rare genetic disorders affecting sugar metabolism.

What to Expect Before the Test

No special preparation is needed unless instructed. For serum/plasma tests, you may need to fast (not eat) for 8–12 hours before the blood draw, but confirm with your provider. Avoid alcohol or strenuous activity 24 hours before.

How the Test Works

Blood is drawn from a vein (usually in your arm) and sent to a lab. The lab uses an immunoassay or enzymatic method to measure glucose and fructose concentrations in your serum or plasma.

What the Results Mean

Glucose results help diagnose diabetes or prediabetes, while fructose levels may indicate fructose malabsorption, genetic disorders, or metabolic stress. Your doctor will interpret results in the context of your symptoms and medical history.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Glucose & Fructose Test

Frequently asked questions

What causes abnormal glucose or fructose levels?
Abnormal results may be due to diabetes, metabolic syndrome, fructose intolerance, liver disease, or certain medications. Lifestyle factors like diet, stress, or physical activity can also influence these levels.
How long will it take to get results?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will contact you once they’re ready for review.
Can I eat or drink before this test?
No, you should fast for 8–12 hours before the blood draw unless your doctor specifies otherwise. Avoid alcohol or heavy exercise 24 hours prior to prevent misleading results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy