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Glucose in Serum (Fasting or Random) with Differential or Fluctuation Analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood sugar levels in serum, sometimes including how they vary over time or compared to previous results.

Quick summary

["Blood sugar levels help monitor diabetes and other conditions affecting glucose metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72650-5
Short code
Glucose ser - peric fld-SCDiff
Synonyms
Glucose ser - peric fld-SCDiff
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to check for diabetes, hypoglycemia (low blood sugar), or to monitor blood sugar trends in people with known conditions like prediabetes or insulin resistance. It may also be used to assess how your body responds to treatments or medications.

What to Expect Before the Test

For a fasting glucose test, you’ll typically fast for 8–12 hours before the blood draw. If it’s a random glucose test, no fasting is required. Bring any medications you’re taking and let your provider know if you have any concerns about fasting.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a small pinch, but it usually doesn’t cause significant discomfort. The blood sample is sent to a lab for analysis.

What the Results Mean

Results may include a single fasting or random glucose value or a comparison of glucose levels at different times (e.g., fasting vs. post-meal). If differential analysis is included, it may show how glucose levels fluctuate over time or between samples.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Glucose Profile (Serum)

Frequently asked questions

What does a high or low glucose level indicate?
High glucose levels may signal diabetes, poor insulin function, or other metabolic disorders. Low glucose levels (hypoglycemia) can cause dizziness, confusion, or fatigue. Your provider will interpret results in the context of your symptoms and medical history.
How often should I get this test?
Frequency depends on your health status. People with diabetes may need tests every few months, while others may only need it once annually or as directed by their provider.
Can I eat or drink before this test?
For fasting tests, avoid food and liquids (except water) for the specified period. For random tests, you can eat and drink normally, but let your provider know if you’re unsure about the protocol.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy