Calculated 24-Hour Urinary Creatinine Clearance
This test measures how well your kidneys filter waste products by calculating your urine output over 24 hours relative to your blood creatinine levels.
["Assesses kidney function by estimating how efficiently your kidneys clear waste from your blood."]
Key facts at a glance
- LOINC
- 105273-7
- Short code
- Gluc RptPeriod Mean Intrstl fld calc
- Synonyms
- Gluc RptPeriod Mean Intrstl fld calc
- Category
- glucose
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- true
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- calculated
- CPT
- 86140
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Creatinine is a waste product from muscle metabolism that your kidneys normally remove from your blood. This test calculates your **creatinine clearance**, which reflects how well your kidneys filter this waste. The result helps determine how effectively your kidneys are working to remove waste and maintain fluid balance.
Why It’s Done
Your doctor may order this test if they suspect kidney disease, monitor kidney function in chronic conditions (like diabetes or high blood pressure), or assess kidney function before certain procedures. It’s also used to guide treatment decisions for conditions affecting kidney function.
How It’s Done
You’ll collect a **24-hour urine sample** (starting after an initial urine void) into a container, returning it to the lab with the collected urine. Blood may also be drawn to measure creatinine levels. The test involves analyzing both urine and blood samples to calculate clearance.
What to Expect
Urine collection requires careful timing—you’ll need to keep the container refrigerated and return it promptly. Blood draws are standard and quick. Follow your doctor’s instructions precisely to ensure accurate results.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
None
Frequently asked questions
How does creatinine clearance differ from a simple blood creatinine test?
What are the typical reference ranges for this test?
Can diet affect creatinine clearance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy