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Glutaconate/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures glutaconate relative to creatinine, helping account for differences in urine concentration.

Quick summary

["This test compares the amount of glutaconate with creatinine in urine to help evaluate metabolic and kidney-related changes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25103-3
Short code
Glutaconate/Creat Ur-sRto
Synonyms
Glutaconate/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of glutaconate in urine compared with the amount of creatinine. Creatinine is a waste product commonly used as a reference for how concentrated a urine sample is.

Why might I need this test?

A clinician may order it as part of an evaluation for a suspected metabolic condition, unexplained symptoms, or monitoring of an existing condition. It may be used with other laboratory and clinical findings.

How is the test performed?

A urine specimen is analyzed in the laboratory, and the glutaconate amount is compared with the creatinine amount. The collection method may be a single urine sample or a timed collection, depending on the order.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory or clinician. For a single-sample collection, a clean-catch midstream urine sample is usually requested; if a timed collection is ordered, all urine collected during the specified period must be included. Do not change diet, supplements, or medications unless instructed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An abnormal result may reflect changes in metabolism, kidney function, hydration, medication or supplement use, or an underlying medical condition. Because urine concentration and collection timing can affect measurements, the ratio is interpreted together with symptoms and other test results. A qualified clinician should explain what any result means in your individual situation.

Short name

Urine glutaconate/creatinine ratio

Frequently asked questions

What does the glutaconate/creatinine ratio show?
It shows the relative amount of glutaconate in urine compared with creatinine. Using creatinine helps reduce the effect of differences in urine concentration.
Does an abnormal result diagnose a specific condition?
No. An abnormal result is nonspecific and must be interpreted with your medical history, symptoms, medications, and other laboratory tests.
How is the urine sample collected?
If a single sample is requested, urine is usually collected clean-catch and midstream. If a timed collection is requested, follow the laboratory's instructions for saving and returning all urine collected during that period.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy