24-Hour Urine Glutamate-to-Creatinine Ratio
Measures urinary glutamate relative to creatinine collected over 24 hours, helping evaluate glutamate excretion while accounting for urine concentration.
["This test measures how much glutamate is excreted in urine relative to creatinine over a full day."]
Key facts at a glance
- LOINC
- 44359-8
- Short code
- Glutamate/Creat 24h Ur
- Synonyms
- Glutamate/Creat 24h Ur
- Category
- kidney
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures the amount of glutamate in a 24-hour urine collection and compares it with the amount of creatinine. Creatinine is used as a reference marker for urine concentration, so the ratio can help describe glutamate excretion even when urine volume varies.
Why might I need this test?
A clinician may order this test when investigating unusual glutamate metabolism, nutritional conditions, kidney handling of amino acids, or symptoms related to a possible metabolic disorder. It may also be used to follow certain treatments or supplement regimens.
How is the test performed?
You collect all urine for exactly 24 hours into a labeled, usually refrigerated, container provided by the laboratory. The laboratory measures glutamate and creatinine in the collection and calculates their ratio.
How do I prepare for the test?
Follow your clinician's instructions about diet, supplements, and medication use. Begin the collection at the time directed, include every urine sample during the next 24 hours, and record the start and finish times. If any sample is missed, ask the laboratory or clinician how to proceed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A higher or lower glutamate-to-creatinine ratio may reflect changes in glutamate intake or supplementation, kidney excretion, or an underlying metabolic condition. Results must be interpreted with symptoms, diet, medications, urine collection quality, and other laboratory findings. An incomplete collection or unusually high urine output can also affect the result.
Short name
24-Hour Urine Glutamate/Creatinine Ratio
Frequently asked questions
Do I need to collect urine for the entire 24 hours?
Why is creatinine included in the test?
Can supplements or diet affect the result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy