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Glutamate/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that compares glutamate with creatinine to help account for differences in urine concentration.

Quick summary

["This ratio shows how much glutamate is present relative to creatinine in a urine sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22711-6
Short code
Glutamate/Creat Ur-sRto
Synonyms
Glutamate/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures glutamate and creatinine in urine and calculates their ratio. Creatinine is used as a reference because urine concentration can vary, while the ratio helps show the relative amount of glutamate.

Why might I need this test?

A clinician may order this test when evaluating a suspected inherited metabolic condition, nutritional concern, or other problem that may affect glutamate metabolism. It may also be used to follow certain treatments over time.

How is the test performed?

A urine sample is collected and analyzed in the laboratory. The amount of glutamate is compared with the amount of creatinine, and the results are reported as a ratio.

How do I prepare for the test?

Follow your clinician's collection instructions, including whether a first-morning or timed urine sample is required. Special diets or fasting are not generally needed unless your healthcare professional specifically directs you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Glutamate/Creatinine Ratio

Frequently asked questions

What does the urine glutamate/creatinine ratio measure?
It measures the amount of glutamate in urine relative to the amount of creatinine. Using creatinine helps reduce the effect of variations in urine concentration.
Does this test require a blood sample?
No. The test is performed using a urine sample collected according to the instructions provided by your clinician or laboratory.
What could cause an abnormal result?
Abnormal results may occur with metabolic disorders, changes in kidney function, diet, medications, or other conditions affecting glutamate. Your clinician will interpret the ratio alongside the rest of your evaluation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy