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Glutamine in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glutamine, a type of amino acid, in your cerebrospinal fluid (the fluid surrounding your brain and spinal cord). Glutamine is involved in brain function and metabolism.

Quick summary

["Understanding glutamine levels in CSF may help assess brain chemistry or identify metabolic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22641-5
Short code
Glutamine CSF-sCnc
Synonyms
Glutamine CSF-sCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like headaches, confusion, seizures, or neurological concerns. It could also be part of a broader evaluation for conditions affecting brain metabolism or fluid balance, such as certain genetic disorders or metabolic syndromes.

What to Expect Before the Test

No special preparation is typically needed. You may receive a local anesthetic to numb the area where the fluid is collected. The procedure involves inserting a needle into your spine to draw a small sample of CSF.

How the Test Is Performed

A healthcare professional will insert a needle into your back to collect CSF. The fluid is then sent to a lab for analysis. The test is usually quick and may cause mild discomfort or soreness afterward.

What the Results Mean

Glutamine levels in CSF can vary based on medical conditions, age, or other factors. Your results will be interpreted by a healthcare provider in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Glutamine CSF

Frequently asked questions

What causes abnormal glutamine levels in CSF?
Abnormal glutamine levels may be linked to metabolic disorders, genetic conditions affecting brain chemistry, or certain neurological disorders. Your provider will consider your symptoms, medical history, and other test results to determine the cause.
How long does it take to get results from this test?
Results are typically available within a few days to a week, depending on lab processing times. Your healthcare provider will contact you once the results are ready.
Can lifestyle changes affect glutamine levels in CSF?
While diet and lifestyle factors can influence blood glutamine levels, CSF glutamine is primarily measured in the context of neurological or metabolic conditions. Your provider will guide you on how to prepare for this specific test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy