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Glutamyltransferase (GGT) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity of glutamyltransferase, an enzyme involved in protein metabolism. It helps assess liver function and detect potential liver damage or disease.

Quick summary

["GGT helps doctors check liver health and identify possible liver issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
80096-1
Short code
Glutamyl-phe SerPl-sCnc
Synonyms
Glutamyl-phe SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Glutamyltransferase (GGT) is an enzyme found in the liver, bile ducts, and other parts of the body. When the liver is damaged, GGT levels can rise. This test specifically measures how much GGT is present in your blood, usually taken from serum or plasma.

Why Is This Test Done?

Doctors may order a GGT test to investigate symptoms like jaundice (yellowing of the skin or eyes), abdominal pain, fatigue, or unexplained liver problems. It can also be used to monitor liver function in people with known liver diseases, such as hepatitis or cirrhosis.

Common Reasons for Testing

Common reasons include evaluating liver health before surgery, checking for alcohol-related liver damage, monitoring liver function in chronic conditions, or diagnosing conditions like bile duct blockages.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 12 hours before the test if it’s part of a liver function panel. Avoid alcohol for 24 hours before the test, as it can affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum/plasma GGT

Frequently asked questions

How high or low are my GGT levels?
GGT levels can vary based on factors like age, sex, medications, and overall health. While elevated GGT often signals liver issues, it can also be influenced by other conditions or medications. Always discuss your results with your healthcare provider for accurate interpretation.
Can I drink alcohol before this test?
No, avoid alcohol for 24 hours before the test. Alcohol can significantly increase GGT levels, making it harder for your doctor to get an accurate reading of your liver function.
Does this test hurt?
No, this test involves a simple blood draw, similar to other routine blood tests. You may feel a slight pinch, but it usually doesn’t cause significant discomfort.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy