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Glutaric Acid in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glutaric acid, a naturally occurring acid, in your cerebrospinal fluid (the fluid surrounding your brain and spinal cord). Elevated levels may suggest certain inherited metabolic disorders.

Quick summary

["Glutaric acid in CSF is checked if symptoms like movement problems or developmental delays appear, especially in children."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54278-7
Short code
Glutarate CSF-sCnc
Synonyms
Glutarate CSF-sCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you or your child show signs of metabolic disorders, such as unusual movement issues, developmental delays, or neurological symptoms. It’s often part of a broader evaluation for conditions like glutaric acidemia, a rare genetic disorder affecting metabolism.

What to Expect Before the Test

No special preparation is needed. The test involves a simple lumbar puncture (spinal tap), where a small amount of CSF is collected via a needle inserted into your lower back. You may feel mild pressure or discomfort, but it’s usually brief.

What the Results Mean

Results are compared to a reference range for healthy individuals. High levels of glutaric acid in CSF can indicate metabolic disorders, while normal levels help rule out these conditions. Your doctor will discuss findings in the context of your symptoms and medical history.

Common Causes of Abnormal Results

Elevated glutaric acid in CSF is most commonly linked to glutaric acidemia, a genetic disorder. Other rare conditions or metabolic imbalances may also be associated with abnormal results, but further testing would be needed to confirm a diagnosis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF Glutaric Acid

Frequently asked questions

What does a high level of glutaric acid in CSF mean?
A high level may suggest a metabolic disorder like glutaric acidemia, which requires genetic testing and specialized medical care. Early diagnosis can help manage symptoms and improve outcomes.
What does a normal level mean?
A normal result helps confirm that your metabolic system is functioning normally and may reduce the need for further testing. However, symptoms you’re experiencing should still be discussed with your doctor.
How often should this test be repeated?
Your doctor will determine if follow-up testing is needed based on your symptoms, test results, and overall health. Repeat testing may be scheduled if symptoms persist or recur.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy