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Glutaric Acid in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glutaric acid, a naturally occurring acid, in your cerebrospinal fluid. Glutaric acid is sometimes elevated in conditions affecting nerve cells or metabolism.

Quick summary

["Elevated levels may signal metabolic disorders or nerve damage."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54280-3
Short code
Glutarylcarn CSF-sCnc
Synonyms
Glutarylcarn CSF-sCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like movement disorders, developmental delays, or neurological issues in children, or if you have a family history of metabolic disorders. It may also be used to monitor certain inherited conditions affecting metabolism or nerve function.

What to Expect During the Test

A small amount of fluid is collected from your spine through a procedure called a lumbar puncture (spinal tap). This is typically done in a hospital or clinic setting. You may feel mild pressure or discomfort during the procedure, but it usually doesn’t cause significant pain.

Preparation for the Test

No special preparation is usually needed. You may be asked to empty your bladder before the procedure. If you’re on blood thinners or have a history of bleeding disorders, your provider may give specific instructions to reduce the risk of bleeding.

What the Results Mean

Results are interpreted by your healthcare provider based on your symptoms, medical history, and other test results. Elevated levels of glutaric acid in CSF can help diagnose or monitor conditions like glutaric aciduria, a rare metabolic disorder.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glutaric acid in CSF is primarily significant in diagnosing or confirming glutaric aciduria, a genetic disorder causing buildup of glutaric acid in the body. High levels may also be associated with other metabolic or neurological conditions that affect nerve cells. Early detection can help guide treatment and management strategies.

Short name

Glutaric Acid (CSF)

Frequently asked questions

What causes elevated glutaric acid levels in CSF?
Elevated levels are most commonly linked to glutaric aciduria, a genetic metabolic disorder. Other conditions, such as certain mitochondrial disorders or other rare metabolic diseases, may also be associated with increased levels. Your healthcare provider will consider your symptoms, family history, and other test results to determine the cause.
How is glutaric acid in CSF tested?
The test involves collecting cerebrospinal fluid through a spinal tap. The fluid is then analyzed in a lab to measure the concentration of glutaric acid using specialized techniques like chromatography or mass spectrometry.
Can this test be done at home?
No, this test requires a medical procedure called a lumbar puncture, which is performed in a clinical setting by a healthcare professional. It is not something you can do at home.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy