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Gluten Immunoglobulin G (IgG) Antibody, Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of antibodies your body produces in response to gluten, a protein found in wheat, barley, and rye. It helps assess potential gluten sensitivity or autoimmune conditions like celiac disease.

Quick summary

["This test helps identify if your immune system reacts to gluten, which may indicate gluten sensitivity or related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102747-3
Short code
Gluten IgG RAST
Synonyms
Gluten IgG RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like stomach pain, bloating, fatigue, or unexplained weight loss, or if you suspect gluten-related issues despite a gluten-free diet. It can also be used to monitor ongoing conditions like celiac disease or non-celiac gluten sensitivity.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw. Wear comfortable clothing and plan to rest after the test. Avoid alcohol and strenuous activity before the procedure.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm using a small needle. The process is quick and typically causes only minor discomfort. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results are not provided as a single numeric range since gluten antibody levels vary widely among individuals. Your provider will interpret the results in the context of your symptoms, medical history, and other tests. Elevated levels may suggest gluten sensitivity or related conditions.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Gluten IgG Antibody

Frequently asked questions

What does a positive test result mean?
A positive result (higher-than-normal antibody levels) suggests your immune system may be reacting to gluten, which could be linked to gluten sensitivity or related conditions. It does not confirm celiac disease alone but may prompt additional testing or dietary evaluation.
Can I eat gluten before the test?
No specific dietary restrictions are required for this test, but if you suspect gluten sensitivity, you may want to discuss your diet with your provider before and after testing to ensure accurate results.
How long does it take to get results?
Results are typically available within a few days to a week, depending on your lab’s processing time. Follow up with your healthcare provider to discuss the results and next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy