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Glucose in Plasma (24-Hour Urine Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) that appears in your urine over a 24-hour period, reflecting how much your body is processing sugar from food.

Quick summary

["Understanding your urine glucose levels helps assess how well your body manages blood sugar."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73358-4
Short code
glyBURIDE ind plt IgM SerPl Ql FC
Synonyms
glyBURIDE ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to check for conditions like diabetes, kidney function, or how well medications (such as glyburide) are working to control blood sugar. It can also help detect hidden sugar in urine, which may indicate poor glucose control.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours, starting after midnight and ending the next midnight. Drink plenty of water to help flush out glucose. Avoid sugary drinks or foods unless instructed otherwise.

How the Test Is Performed

Urine is collected in a container over the 24-hour period. The sample is then sent to a lab for analysis using a specialized method to measure glucose concentration.

Possible Results and Interpretation

Results are typically reported as the total amount of glucose excreted in urine (in mg or grams). High levels may suggest diabetes or other metabolic issues, while normal levels indicate proper glucose metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Glucose in urine can signal diabetes if present in significant amounts, as the kidneys struggle to filter out excess sugar. It may also reflect poorly controlled blood sugar from diabetes or other conditions like kidney disease. Regular monitoring helps manage these conditions effectively.

Frequently asked questions

What does a positive result mean?
A positive result (glucose detected in urine) often means your body isn’t processing sugar efficiently, which could be linked to diabetes or other metabolic issues. Your provider will discuss next steps based on your overall health.
How does this test differ from a blood glucose test?
This test measures glucose in urine over 24 hours, while a blood glucose test checks current blood sugar levels. Urine tests can reveal long-term sugar handling, whereas blood tests show real-time levels.
Avoid sugary drinks like coffee or tea with added sweeteners. Stick to plain water unless your provider specifies otherwise to ensure accurate results.
A 24-hour urine test provides a full picture of how much glucose your body processes daily, giving a clearer picture of glucose metabolism than a single sample.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy