Skip to content

Glycine concentration in serum or plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glycine, an amino acid, in your blood. Glycine plays a role in protein synthesis, metabolism, and other important bodily functions.

Quick summary

["Understanding glycine levels can help identify metabolic or liver-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26929-0
Short code
Glycine Amn-sCnc
Synonyms
Glycine Amn-sCnc
Category
glucose
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Glycine Does in Your Body

Glycine is a simple amino acid that helps build proteins, supports nerve function, and aids in energy production. Your body naturally produces it, but certain health issues may affect its balance in your blood.

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, muscle weakness, or signs of metabolic disorders. It could also be part of a broader evaluation for liver disease, kidney problems, or other metabolic conditions.

How the Test Works

A small blood sample is taken, usually from your arm. The sample is then analyzed in a lab to measure glycine levels using a specialized technique, such as high-performance liquid chromatography (HPLC).

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours if your provider suggests it. Wear comfortable clothing and plan to stay for the blood draw.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal glycine levels may indicate underlying health issues, such as liver disease, kidney problems, or certain metabolic disorders. Low glycine could suggest liver dysfunction, while very high levels might be linked to metabolic imbalances or rare genetic conditions. Always discuss results with your healthcare provider.

Short name

Serum Glycine Level

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you once they have the results.
What are the normal ranges for glycine?
Normal glycine levels vary by lab and individual, so reference ranges are not universally standardized. Your provider will interpret the results in relation to your health status and medical history.
Can diet affect glycine levels?
Dietary glycine is found in animal proteins, but your body produces it naturally. While diet may influence glycine metabolism indirectly, it’s not a primary factor in test results. Always follow your provider’s advice on dietary restrictions if recommended.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy