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Serum Glycine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glycine, an amino acid found in your blood, which plays a role in protein synthesis and metabolism.

Quick summary

["Understanding your glycine levels may help assess certain metabolic or liver conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30066-5
Short code
Glycine/Creat Ur-Rto
Synonyms
Glycine/Creat Ur-Rto
Category
glucose
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, muscle weakness, or unexplained metabolic issues. It could also be part of a broader evaluation for conditions affecting protein metabolism or liver function.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the test if it’s part of a metabolic panel, but this depends on your provider’s instructions. Bring any medications you’re currently taking.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The blood sample is then sent to a lab for analysis. The test typically takes a few minutes, and you can usually return to your normal activities afterward.

What the Results Mean

Results are interpreted by your healthcare provider based on your overall health and medical history. Abnormal levels may suggest conditions like glycine encephalopathy, liver disease, or other metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Glycine Level

Frequently asked questions

What Does It Measure?
Glycine is an essential amino acid involved in the synthesis of other compounds, including creatine and glutathione. Low levels may indicate metabolic disorders or liver dysfunction, while high levels could be associated with certain genetic conditions or kidney issues.
How Often Should I Get This Test?
Your provider will determine the frequency based on your health status and symptoms. Regular monitoring may be needed if you have a known metabolic disorder or ongoing medical conditions.
Can I Eat or Drink Before the Test?
Follow your provider’s instructions, but generally, you can eat a normal meal unless specified otherwise. Some tests may require fasting, so check with them beforehand.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy