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Glycine concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glycine, an essential amino acid, in your blood. Glycine plays a role in protein synthesis, metabolism, and helps maintain normal fluid balance.

Quick summary

["Glycine levels can help diagnose or monitor certain metabolic conditions or kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47639-0
Short code
Glycine SFr Spec
Synonyms
Glycine SFr Spec
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test if you have symptoms or conditions that could be linked to glycine metabolism, such as unexplained muscle weakness, metabolic disorders, or kidney issues. It may also be part of a broader evaluation for genetic or inherited metabolic diseases.

What Does This Test Involve?

A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis using a specialized method to measure glycine levels accurately.

What Are Possible Results?

Results are typically reported as a concentration value (e.g., milligrams per deciliter or micromoles per liter). Your actual results will be compared to a reference range provided by your healthcare provider, who will interpret them in the context of your overall health.

What Does It Mean If My Results Are Abnormal?

Abnormal glycine levels can indicate underlying health issues, such as glycine-related metabolic disorders, kidney problems, or other conditions affecting amino acid metabolism. Your provider will discuss these findings with you and may recommend further testing or adjustments to your treatment plan.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum/plasma glycine

Frequently asked questions

How often will I need this test?
The frequency of this test depends on your health condition and treatment plan. If you have a known metabolic disorder or kidney condition, your provider may order it regularly. Otherwise, it might be done only if symptoms or other test results suggest a need for monitoring.
What do I need to do to prepare for this test?
No special preparation is usually required, but avoid eating or drinking anything (except water) for several hours before the test if instructed by your healthcare provider. Wear comfortable clothing and plan to stay near the testing site for a short time after the blood draw.
Can I take this test while pregnant?
Yes, this test can be performed during pregnancy if medically necessary. However, always inform your healthcare provider about any medications you are taking or if you have any concerns, as they may adjust your care plan accordingly.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy