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Asialo-IgG (Serum) Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of asialo-IgG (a form of immunoglobulin G that lacks certain sugar molecules) in your serum. It may be used to assess liver function or detect certain metabolic conditions.

Quick summary

["This test helps evaluate liver enzyme activity and potential metabolic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88723-2
Short code
GM1 Asialo IgG+IgM Ser IA-aCnc
Synonyms
GM1 Asialo IgG+IgM Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to liver dysfunction, such as jaundice, fatigue, or unexplained weight loss. It could also be part of a broader evaluation for metabolic or genetic disorders affecting protein processing.

What to Expect Before the Test

No special preparation is typically required. You may fast for 8–12 hours before the draw if instructed, but always follow your provider’s instructions. Bring any medications or supplements you’re taking to discuss with them beforehand.

How the Test Works

Blood is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure the concentration of asialo-IgG. The process involves separating serum from blood cells and applying specialized biochemical techniques to detect the analyte.

What the Results Mean

Results are interpreted in the context of your overall health, symptoms, and medical history. Elevated levels may suggest liver disease or other metabolic issues, while lower levels could indicate normal or less affected processing of proteins.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Asialo-IgG Serum Level

Frequently asked questions

What Does This Test Measure?
This test specifically measures the presence of asialo-IgG, a form of IgG that lacks terminal sialic acid residues. Asialo-IgG is a marker that can be elevated in conditions affecting liver glycosylation (the addition of sugar molecules) or certain hereditary metabolic disorders.
What Are Common Causes of Abnormal Results?
Abnormal results may be associated with liver diseases (e.g., cirrhosis, hepatitis), certain genetic disorders (e.g., alpha-1 antitrypsin deficiency), or conditions affecting protein metabolism. Always discuss results with your provider for personalized interpretation.
How Often Should This Test Be Done?
Frequency depends on your diagnosis and symptoms. If this test is part of routine monitoring (e.g., for liver disease), your provider will outline a schedule. If it’s for a specific condition, follow their guidance for follow-up testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy