Ganglioside GM1 Serum Concentration (Mass Concentration)
This test measures the amount of GM1 ganglioside, a complex sugar molecule found in your blood serum. It may be ordered to help diagnose or monitor certain neurological conditions.
["GM1 ganglioside levels can provide clues about nerve cell health in rare genetic disorders."]
Key facts at a glance
- LOINC
- 31500-2
- Short code
- GM1 Gangl IgG+IgM Ser-aCnc
- Synonyms
- GM1 Gangl IgG+IgM Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like muscle weakness, developmental delays, or neurological issues. It could also be part of a broader evaluation for conditions like GM1 gangliosidosis, a rare inherited disorder affecting nerve cells.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. It usually takes about 15 minutes. Avoid eating or drinking for 2–3 hours before the test if instructed.
What the Test Results Mean
Results are interpreted by your doctor based on your symptoms and medical history. Elevated levels may suggest a genetic disorder affecting nerve cells, while normal levels help rule out certain conditions.
Common Conditions Monitored
This test is primarily used in the diagnosis and monitoring of GM1 gangliosidosis and related lysosomal storage disorders. It may also be part of genetic testing for inherited metabolic diseases.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
GM1 ganglioside is a marker for lysosomal storage disorders, where enzymes break down GM1 ganglioside normally. Abnormal accumulation can cause progressive neurological damage. Early detection through blood testing helps guide treatment decisions and management strategies.
Short name
GM1 Ganglioside Level
Frequently asked questions
What causes abnormal GM1 ganglioside levels?
How is this test different from other blood tests?
Can diet affect GM1 levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy