Immunoglobulin G (IgG) Subclass 1, Serum Concentration
This test measures the amount of Immunoglobulin G (IgG) subclass 1, a type of antibody in your blood. IgG1 is one of the main components of your immune system, helping fight infections and diseases.
["IgG1 helps protect your body by identifying and neutralizing harmful substances."]
Key facts at a glance
- LOINC
- 108198-3
- Short code
- GM4 IgG+IgM Ser Ql IA
- Synonyms
- GM4 IgG+IgM Ser Ql IA
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
IgG1 is part of the broader immunoglobulin family, which includes antibodies that play a critical role in your immune response. This test specifically looks at the concentration of IgG1 in your serum, which can vary depending on your health status, immune function, and exposure to infections or vaccines.
Why Might You Need This Test?
Doctors may order an IgG1 test to evaluate immune function, diagnose conditions like immunodeficiency, assess response to treatments, or investigate symptoms such as frequent infections, fatigue, or autoimmune issues. It can also help monitor certain chronic diseases or immune-related disorders.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum, which is sent to a lab for analysis. The lab uses an immunoassay method to measure the IgG1 concentration.
What Are Possible Results?
Results are typically reported as a concentration value in milligrams per deciliter (mg/dL) or grams per liter (g/L). While specific reference ranges can vary by lab, lower than expected levels may indicate immune deficiencies, while higher levels might be seen in chronic infections or certain autoimmune conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
IgG1 levels can be useful in diagnosing or managing conditions affecting the immune system. For example, low IgG1 levels might suggest a primary immunodeficiency, while abnormal levels can help guide treatment decisions, such as adjusting immune-boosting therapies or identifying underlying infections.
Short name
IgG1 Level
Frequently asked questions
What does a low IgG1 level mean?
What causes elevated IgG1 levels?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy